Chembl77804


SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1CNC(=O)NC12CC3CC(CC(C3)C1)C2
InChIKey FYXKKUVBYAGWKK-VIJVRHQBSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 4
Rotatable bonds 6
Molecular weight (Da) 530.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Human Opioid A pIC50 9.54 9.54 9.54 ChEMBL
κ OPRK Human Opioid A pIC50 8.39 8.39 8.39 ChEMBL
κ OPRK Human Opioid A pEC50 7.94 7.94 7.94 ChEMBL
μ OPRM Human Opioid A pIC50 8.96 8.96 8.96 ChEMBL