CHEMBL599135


SMILES CN1CCc2cc(Cl)c(O)cc2[C@H]2c3cccc(/C=N/OCc4ccccc4)c3CC[C@@H]21
InChIKey YUNGHULYKDVTOC-JJQUOXMWSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 446.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 8.6 8.6 8.6 ChEMBL
D1 DRD1 Human Dopamine A pKi 9.7 9.7 9.7 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.08 5.08 5.08 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.16 7.16 7.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database