CHEMBL590580


SMILES Cc1cccc2c1C(=O)NC1CCNCCN21
InChIKey IDTOIAGIXRXDMI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 0
Molecular weight (Da) 231.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.0 8.0 8.0 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.54 8.54 8.54 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.85 6.85 6.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pEC50 7.21 7.21 7.21 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.21 7.21 7.21 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.7 8.7 8.7 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 7.16 7.16 7.16 ChEMBL