CHEMBL603872


SMILES COc1ccc(-c2cccc3c2CC[C@H]2[C@H]3c3cc(O)c(Cl)cc3CCN2C)cc1
InChIKey PZVTYIIWLUKKIK-AZGAKELHSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 419.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D5 DRD5 Human Dopamine A pKi 8.21 8.21 8.21 ChEMBL
D1 DRD1 Human Dopamine A pKi 9.15 9.15 9.15 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.0 5.0 5.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.26 6.26 6.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database