CHEMBL5221670


SMILES COc1ccc(N2CCN(CCCN3C(=O)CCc4ccccc43)CC2)cc1
InChIKey IPZLHIDFKOMHRW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 379.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.16 8.16 8.16 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.08 5.08 5.08 ChEMBL
D2 DRD2 Human Dopamine A pKi 4.68 4.68 4.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 6.41 6.65 6.97 ChEMBL