Chembl87458

Chemical Properties

SMILES O=C(c1ccc(F)cc1)C1CCN(CCC2Cc3cc(F)ccc3C2=O)CC1
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight 383.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey OWXLOVODAGXFLI-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Rat 5-Hydroxytryptamine A pKd 6.12 6.12 6.12 ChEMBL
D1 DRD1 Rat Dopamine A pKi 5.96 5.96 5.96 ChEMBL
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 8.42 8.42 8.42 ChEMBL
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKd 8.12 8.12 8.12 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.32 7.32 7.32 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.08 6.08 6.08 ChEMBL