CHEMBL52604


SMILES CCn1c(=O)n([C@@H]2CCN3[C@H](c4ccccc4)CCC[C@@H]3C2)c2ccccc21
InChIKey RTCXPSZQJKHURF-NJYVYQBISA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 375.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 7.71 7.71 7.71 ChEMBL
δ OPRD Human Opioid A pKi 5.83 5.83 5.83 ChEMBL
κ OPRK Human Opioid A pKi 7.64 7.64 7.64 ChEMBL
μ OPRM Human Opioid A pKi 8.6 8.6 8.6 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database