CHEMBL60815


SMILES c1ccc(-c2c[nH]c(CN3CCN(c4ccccc4)CC3)c2)cc1
InChIKey YLPJQEDKFKCTSE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 317.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Pig 5-Hydroxytryptamine A pKi 5.89 5.89 5.89 ChEMBL
D1 DRD1 Pig Dopamine A pKi 5.68 5.68 5.68 ChEMBL
D1 DRD1 Bovine Dopamine A pKi 5.68 5.68 5.68 ChEMBL
D4 DRD4 Human Dopamine A pKi 7.92 7.92 7.92 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.1 6.1 6.1 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.27 6.28 6.29 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.64 6.71 6.77 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 8.17 8.17 8.17 ChEMBL