PALTUSOTINE
SMILES | N#Cc1cccc(-c2ccc3ncc(-c4cc(F)cc(F)c4)c(N4CCC(N)CC4)c3c2)c1O |
InChIKey | GHILNKWBALQPDP-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 2 |
Rotatable bonds | 3 |
Molecular weight (Da) | 456.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Structure pdb | 7YAC |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
SST2 | SSR2 | Dog | Somatostatin | A | pEC50 | 8.18 | 8.18 | 8.18 | ChEMBL |
SST2 | SSR2 | Rat | Somatostatin | A | pEC50 | 8.92 | 8.92 | 8.92 | ChEMBL |
SST4 | SSR4 | Human | Somatostatin | A | pEC50 | 6.0 | 6.0 | 6.0 | ChEMBL |
SST2 | SSR2 | Human | Somatostatin | A | pEC50 | 9.6 | 9.6 | 9.6 | ChEMBL |