CHEMBL608530


SMILES CN1CCCC[C@H]1CCN1c2ccccc2Sc2ccc([S+](C)[O-])cc21
InChIKey SLVMESMUVMCQIY-AJWVYOOVSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 386.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.15 6.27 6.39 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.71 5.96 6.21 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.4 6.43 6.46 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.71 6.87 7.02 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.37 6.45 6.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pIC50 5.9 5.9 5.9 ChEMBL
D2 DRD2 Human Dopamine A pIC50 5.93 6.0 6.08 ChEMBL