CHEMBL53325


SMILES COc1cccc2c1CCCC2CCCN1CCN(C2CCCCC2)CC1
InChIKey PHRCDWVPTULQMT-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 370.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2B ADA2B Human Adrenoceptors A pKi 5.03 5.03 5.03 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.45 5.45 5.45 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.32 6.32 6.32 ChEMBL
M4 ACM4 Human Acetylcholine (muscarinic) A pKi 5.4 5.4 5.4 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 4.71 4.71 4.71 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.22 6.22 6.22 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.54 7.54 7.54 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.82 5.82 5.82 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.32 5.32 5.32 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 4.63 4.63 4.63 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database