CHEMBL538307


SMILES O=C(C1CC1c1cccnc1)C12CC3CC(CC(C3)C1)C2
InChIKey BLSINDLRTIRLFV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 281.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 4.64 4.64 4.64 ChEMBL
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 5.15 5.15 5.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database