CHEMBL552268


SMILES COc1ccccc1N1CCN(Cc2cc3c(=O)[nH]c(N(C)C)nc3[nH]2)CC1
InChIKey OIAXKPXJNIOPBF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 5
Molecular weight (Da) 382.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.08 5.08 5.08 ChEMBL
D4 DRD4 Human Dopamine A pKi 8.62 8.62 8.62 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.02 6.02 6.02 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.77 6.83 6.89 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.77 6.83 6.89 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 6.02 6.02 6.02 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database