CHEMBL55319


SMILES O=C1CC2(CCCC2)CC(=O)N1CCCN1CCN(c2cc(Cl)ccc2Cl)CC1
InChIKey SYPZJTHVWQUCJS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 437.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 8.76 8.76 8.76 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 7.87 7.87 7.87 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 8.54 8.54 8.54 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.4 6.4 6.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database