CHEMBL610281


SMILES Oc1ccc2c3c1O[C@H]1[C@@H](I)CC[C@@]4(O)[C@@H](C2)N(CC2CC2)CC[C@]314
InChIKey XEXVJJBUTPOPFH-LRLHPVAZSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 453.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pKi 8.07 8.45 8.83 ChEMBL
μ OPRM Rat Opioid A pKi 8.68 8.73 8.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
κ OPRK Guinea pig Opioid A pIC50 7.62 8.06 8.5 ChEMBL
μ OPRM Rat Opioid A pIC50 8.14 8.25 8.36 ChEMBL