CHEMBL69700


SMILES COc1cc(C[C@@H](C)N)c(OC)cc1Br
InChIKey FXMWUTGUCAKGQL-SSDOTTSWSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 273.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 7.3 7.3 7.3 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 5.21 5.21 5.21 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.54 9.54 9.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TA1 TAAR1 Human Trace amine A pEC50 4.5 4.5 4.5 ChEMBL
TA1 TAAR1 Rhesus macaque Trace amine A pEC50 4.86 4.86 4.86 ChEMBL