CHEMBL556070


SMILES O=C(C1CC1c1ccc(N2CCOCC2)nc1)C12CC3CC(CC(C3)C1)C2
InChIKey SUCUNCCEKWWUHL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 366.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 7.62 7.62 7.62 ChEMBL
mGlu1 GRM1 Human Metabotropic glutamate C pKi 6.96 6.96 6.96 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 4.56 4.56 4.56 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database