CHEMBL61789


SMILES COc1c(C(=O)NCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)cc(Br)c2ccccc12
InChIKey LGTFCCLATINIEE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 563.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.99 8.14 8.3 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.97 6.97 6.97 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.87 6.03 6.19 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.42 5.42 5.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database