CHEMBL566379


SMILES O=C1Cc2c(ccc3c2OC[C@H](CNCCCC2CCc4c([nH]c5ccc(F)cc45)C2)O3)N1
InChIKey OTCAUALNGZOKLN-LWKPJOBUSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 6
Molecular weight (Da) 449.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.21 6.3 6.4 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.22 8.22 8.22 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.3 7.32 7.35 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database