CHEMBL566508


SMILES CSc1ncc2c(n1)CC(CN1CCC(c3noc4cc(F)ccc34)CC1)CC2=O
InChIKey FNRRHBXSSQNLPH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 426.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 7.48 7.48 7.48 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.35 7.35 7.35 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.34 8.34 8.34 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.49 7.49 7.49 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database