CHEMBL68740


SMILES O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cc2cc(F)ccc2[nH]1
InChIKey IMCPEGAWOYJDMH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 462.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.59 8.59 8.59 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.08 7.08 7.08 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.28 9.41 9.55 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.27 6.27 6.27 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.43 7.43 7.43 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 7.28 7.28 7.28 ChEMBL
D2 DRD2 Human Dopamine A pIC50 6.25 6.25 6.25 ChEMBL