CHEMBL78190


SMILES COc1cc(C)c(Nc2ncc[nH]2)cc1C(C)(C)C
InChIKey QELYRGGNEIAOKD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 259.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α2A ADA2A Human Adrenoceptors A pKi 7.41 7.41 7.41 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.54 6.54 6.54 ChEMBL
α2B ADA2B Rat Adrenoceptors A pKi 6.42 6.42 6.42 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database