Chembl3580749


SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CCCCNC(=O)C[C@@H](C(N)=O)NC(=O)[C@H](Cc2ccc(F)cc2F)NC(=O)[C@H](Cc2ccccc2)NC1=O
InChIKey JMEAERPFLWHOHL-WUXKFAKNSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Protein
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
δ OPRD Rat Opioid A pIC50 7.95 7.95 7.95 ChEMBL
κ OPRK Guinea pig Opioid A pIC50 9.52 9.52 9.52 ChEMBL
μ OPRM Rat Opioid A pIC50 9.31 9.31 9.31 ChEMBL
δ OPRD Human Opioid A pEC50 8.06 8.06 8.06 ChEMBL
κ OPRK Human Opioid A pEC50 8.87 8.87 8.87 ChEMBL
μ OPRM Human Opioid A pEC50 8.78 8.78 8.78 ChEMBL