CHEMBL88365
SMILES | Oc1cccc(N2CCN(Cc3ccccc3)CC2)c1 |
InChIKey | BISVFNHMXVNVMG-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 1 |
Rotatable bonds | 3 |
Molecular weight (Da) | 268.2 |
Drug properties
Molecular type | Small molecule |
Physiological/Surrogate | Surrogate |
Approved drug | No |
Database connections
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
D2 | DRD2 | Rat | Dopamine | A | pKi | 6.61 | 7.49 | 8.26 | ChEMBL |
D3 | DRD3 | Human | Dopamine | A | pKi | 7.54 | 7.54 | 7.54 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 6.61 | 7.12 | 8.34 | ChEMBL |
D2 | DRD2 | Human | Dopamine | A | pKi | 6.94 | 7.64 | 8.34 | PDSP Ki database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |