CHEMBL594717


SMILES Cc1ccc(F)cc1CO[C@H]1CCc2ccc(N3CCNC[C@H]3C)nc21
InChIKey ZAZVLBZIEZHJFV-BEFAXECRSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 355.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.11 8.11 8.11 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.82 8.82 8.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 7.55 7.55 7.55 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 6.25 6.25 6.25 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pIC50 8.72 8.72 8.72 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 8.47 8.47 8.47 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pIC50 7.34 7.34 7.34 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.2 6.2 6.2 ChEMBL