CHEMBL604102


SMILES N[C@@H]1CCN(c2ccc3[nH]nc(S(=O)(=O)c4cccc5ccccc45)c3c2)C1
InChIKey OPTAOWZLDMSBKX-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 392.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.22 5.22 5.22 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 5.64 5.64 5.64 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 8.35 8.35 8.35 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 6.56 6.56 6.56 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.33 5.33 5.33 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.54 5.54 5.54 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 7.8 7.8 7.8 ChEMBL