Nomifensine

Chemical Properties

SMILES CN1CC(C2=C(C1)C(=CC=C2)N)C3=CC=CC=C3
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight 238.1

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey XXPANQJNYNUNES-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pKi 4.0 4.0 4.0 PDSP KiDatabase
D2 DRD2 Human Dopamine A pKi 4.0 4.0 4.0 PDSP KiDatabase
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.93 4.93 4.93 PDSP KiDatabase
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 5.0 5.16 5.43 PDSP KiDatabase
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 4.0 4.5 5.0 PDSP KiDatabase
H1 HRH1 Rat Histamine A pKi 4.0 5.23 6.46 PDSP KiDatabase
H1 HRH1 Human Histamine A pKi 4.57 4.57 4.57 PDSP KiDatabase
D2 DRD2 Rat Dopamine A pKi 4.0 4.0 4.0 PDSP KiDatabase
D1 DRD1 Rat Dopamine A pKi 4.0 4.0 4.0 PDSP KiDatabase
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 4.0 4.0 4.0 PDSP KiDatabase