Reboxetine

Chemical Properties

SMILES CCOC1=CC=CC=C1OC(C2CNCCO2)C3=CC=CC=C3
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight 313.2

Drug Properties

Type Small molecule
Endogenous No
Approved No
InChIKey CBQGYUDMJHNJBX-UHFFFAOYSA-N

Database Connections

External Links


Bioactivity

Receptor Experimental Data Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 4.0 4.0 4.0 PDSP KiDatabase
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 4.0 4.0 4.0 PDSP KiDatabase
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 4.0 4.0 4.0 PDSP KiDatabase
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 4.0 4.0 4.0 PDSP KiDatabase
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.34 5.34 5.34 PDSP KiDatabase
α1A ADA1A Human Adrenoceptors A pKi 4.0 4.0 4.0 PDSP KiDatabase
α2A ADA2A Human Adrenoceptors A pKi 4.0 4.0 4.0 PDSP KiDatabase
D2 DRD2 Human Dopamine A pKi 4.0 4.0 4.0 PDSP KiDatabase
D3 DRD3 Human Dopamine A pKi 4.0 4.0 4.0 PDSP KiDatabase