CHEMBL611207


SMILES CN1CCCC[C@@H]1CCN1c2ccccc2Sc2ccc([S+](C)[O-])cc21
InChIKey SLVMESMUVMCQIY-DIERRCTGSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 386.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.38 6.67 6.95 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.5 6.75 6.99 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.58 7.61 7.64 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.98 7.09 7.19 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.74 7.28 8.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Human Dopamine A pIC50 6.34 6.6 6.86 ChEMBL
D2 DRD2 Human Dopamine A pIC50 7.11 7.16 7.2 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 5.3 5.3 5.3 ChEMBL