(R)-4-(3-(2-Amino-4-(4-Fluorophenyl)Thiazol-5-Yl)Pyrrolidin-1-Yl)-1-(4-Fluorophenyl)Butan-1-One


SMILES C1CN(CC1C2=C(N=C(S2)N)C3=CC=C(C=C3)F)CCCC(=O)C4=CC=C(C=C4)F
InChIKey PMIAIKWRXUGRQG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 427.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.72 7.72 7.72 PDSP Ki database