Endo-8-(1h-Indol-3-Ylmethyl)-3-(4-Chlorophenyl)-8-Azabicyclo-[3.2.1]Octan-3-Ol


SMILES C1CC2CC(CC1N2CC3=CNC4=CC=CC=C43)(C5=CC=C(C=C5)Cl)O
InChIKey AXPWNFAVTPIWHV-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 366.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivity

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pKi 6.6 6.6 6.6 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 5.8 5.8 5.8 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 4.52 4.52 4.52 PDSP Ki database