CHEMBL612083


SMILES CCCN(CCc1ccccc1)[C@H]1CCc2c(O)cccc2C1
InChIKey DEYFWGXTPWNADC-IBGZPJMESA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 309.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKd 7.05 7.61 8.0 ChEMBL
D1 DRD1 Human Dopamine A pKi 5.92 6.28 6.64 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.7 8.19 8.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 5.55 5.92 6.3 ChEMBL
TSH TSHR Human Glycoprotein hormone A Potency 4.9 4.9 4.9 ChEMBL