CHEMBL62996


SMILES Oc1ccc(Br)cc1-c1nc(CN2CCN(c3ccccc3)CC2)co1
InChIKey RXGOETNYBNUSSO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 413.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.76 4.76 4.76 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.24 6.24 6.24 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.12 5.12 5.12 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.18 5.27 5.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database