CHEMBL64072


SMILES COCc1cccc(C[C@H](O)/C=C/[C@H]2[C@H](O)C[C@@H](F)[C@@H]2CCSCCCC(=O)O)c1
InChIKey IZHJCSHFOPUFEW-WJLXUBJISA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 13
Molecular weight (Da) 440.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP2 PE2R2 Mouse Prostanoid A pKi 5.51 5.51 5.51 ChEMBL
EP4 PE2R4 Mouse Prostanoid A pKi 7.5 7.5 7.5 ChEMBL
EP3 PE2R3 Mouse Prostanoid A pKi 5.82 5.82 5.82 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
EP4 PE2R4 Mouse Prostanoid A pEC50 6.57 6.57 6.57 ChEMBL