CHEMBL64325


SMILES COc1ccc(Br)cc1-c1nc(CN2CCN(c3ccccc3)CC2)cs1
InChIKey IOPFZPQJWJQACY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 443.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.9 5.9 5.9 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.23 6.23 6.23 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.92 5.92 5.92 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.21 6.29 6.36 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database