CHEMBL70563


SMILES CS(=O)(=O)c1cc(Cl)ccc1NCC1=NCCN1
InChIKey RNPCNKHTEISXAL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 287.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1B ADA1B Human Adrenoceptors A pKi 6.19 6.19 6.19 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 6.06 6.06 6.06 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 5.4 5.4 5.4 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 6.34 6.34 6.34 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 5.3 5.3 5.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pEC50 6.29 6.29 6.29 ChEMBL