ADENOSINE PHOSPHATE


SMILES Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O
InChIKey UDMBCSSLTHHNCD-KQYNXXCUSA-N

Chemical properties

Hydrogen bond acceptors 10
Hydrogen bond donors 5
Rotatable bonds 4
Molecular weight (Da) 347.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A3 AA3R Rat Adenosine A pKi 7.76 7.76 7.76 PDSP Ki database
A2A AA2AR Rat Adenosine A pKi 7.24 7.24 7.24 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
P2Y11 P2Y11 Human P2Y A pEC50 4.76 4.76 4.76 ChEMBL
P2Y1 P2RY1 Wild turkey P2Y A pEC50 5.46 5.5 5.55 ChEMBL
P2Y2 P2RY2 Human P2Y A pEC50 5.43 6.25 7.07 ChEMBL
P2Y1 P2RY1 Human P2Y A pEC50 5.14 5.48 5.82 ChEMBL
RXFP1 RXFP1 Human Relaxin family peptide A Potency 4.65 4.65 4.65 ChEMBL
A1 AA1R Human Adenosine A pEC50 6.3 6.3 6.3 ChEMBL