CHEMBL5081245


SMILES CCC(=O)N(c1ccc(Cl)c(Cl)c1)C1CCN(C(=O)[C@H](Cc2ccc(Cl)cc2)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc2ccc(O)cc2)CC1
InChIKey SJPRZPOIXMISSI-PDXWSVEKSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Na
Endogenous/Surrogate Surrogate
Approved drug No

Database connections


Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pKi 8.29 8.29 8.29 ChEMBL
δ OPRD Human Opioid A pKi 8.96 8.96 8.96 ChEMBL
κ OPRK Human Opioid A pKi 7.33 7.33 7.33 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pIC50 7.93 7.93 7.93 ChEMBL
δ OPRD Human Opioid A pIC50 8.63 8.63 8.63 ChEMBL
κ OPRK Human Opioid A pIC50 6.72 6.72 6.72 ChEMBL