CHEMBL88435


SMILES Cc1ccccc1N1CCN(CCCNc2ncccc2C(=O)N(C)C)CC1
InChIKey PLJCELRWRGZCMC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 381.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Rabbit Adrenoceptors A pKd 8.7 8.7 8.7 ChEMBL
α1A ADA1A Bovine Adrenoceptors A pKi 9.1 9.1 9.1 ChEMBL
α1D ADA1D Rat Adrenoceptors A pKd 8.0 8.0 8.0 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database