JWH-133


SMILES CCCC(c1ccc2c(c1)OC([C@H]1[C@H]2CC(=CC1)C)(C)C)(C)C
InChIKey YSBFLLZNALVODA-RBUKOAKNSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 312.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Human Cannabinoid A pKi 8.5 8.5 8.5 Guide to Pharmacology
CB1 CNR1 Rat Cannabinoid A pKi 6.17 6.17 6.17 ChEMBL
CB2 CNR2 Human Cannabinoid A pKi 6.85 8.47 10.64 ChEMBL
CB1 CNR1 Human Cannabinoid A pKi 6.17 6.51 9.1 ChEMBL
CB1 CNR1 Mouse Cannabinoid A pKi 6.34 6.34 6.34 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB1 CNR1 Rat Cannabinoid A pEC50 5.7 5.7 5.7 ChEMBL
CB2 CNR2 Human Cannabinoid A pEC50 6.41 7.22 8.4 ChEMBL
CB2 CNR2 Human Cannabinoid A pIC50 6.26 6.67 7.09 ChEMBL