CHEMBL91553


SMILES Cc1c(-c2ccccn2)nc(O)n1C1CCN(Cc2ccccc2)CC1
InChIKey HCOQJKDXIVIYQF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 348.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.35 8.35 8.35 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.92 5.92 5.92 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.57 6.57 6.57 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database