Thioproperazine


SMILES CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)S(=O)(=O)N(C)C.CS(=O)(=O)O.CS(=O)(=O)O
InChIKey QPMDKXBBAVQDCB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 10
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 638.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 9.35 9.35 9.35 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 8.92 8.92 8.92 PDSP Ki database
D3 DRD3 Rat Dopamine A pKi 8.77 8.77 8.77 PDSP Ki database
D2 DRD2 Rat Dopamine A pKi 9.68 9.68 9.68 PDSP Ki database
D4 DRD4 Rat Dopamine A pKi 7.28 7.28 7.28 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 8.03 8.03 8.03 Drug Central
D3 DRD3 Human Dopamine A pKi 8.05 8.05 8.05 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database