GPCRdb

tyramine

SMILES	NCCc1ccc(cc1)O
InChIKey	DZGWFCGJZKJUFP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors	2
Hydrogen bond donors	2
Rotatable bonds	2
Molecular weight (Da)	137.1

Drug properties

Molecular type	Small molecule
Physiological/Surrogate	Endogenous
Approved drug	Yes

Database connections

Guide To Pharmacology DrugBank Drug Central ChEMBL_compound_ids PubChem GPCRdb
Ligand site mutations	D₂

Bioactivities

Affinity
Potency

Search:

Receptor					Activity				Source
GTP No matches found	Uniprot No matches found	Species No matches found	Family No matches found	Class No matches found	Type No matches found	Min	Avg	Max	Database No matches found
5-HT_2B	5HT2B	Rat	5-Hydroxytryptamine	A	pKd	5.1	5.1	5.1	ChEMBL
TA₁	TAAR1	Human	Trace amine	A	pKd	7.7	7.7	7.7	Guide to Pharmacology
TA₁	TAAR1	Rat	Trace amine	A	pKi	7.2	7.2	7.2	Guide to Pharmacology
TA₁	TAAR1	Mouse	Trace amine	A	pKi	6.4	6.4	6.4	Guide to Pharmacology
TA₁	TAAR1	Human	Trace amine	A	pKi	7.47	7.47	7.47	PDSP Ki database

Showing 1 to 5 of 5 entries

Search:

Receptor					Activity				Source
GTP No matches found	Uniprot No matches found	Species No matches found	Family No matches found	Class No matches found	Type No matches found	Min	Avg	Max	Database No matches found
M₁	ACM1	Rat	Acetylcholine (muscarinic)	A	Potency	7.3	7.3	7.3	ChEMBL
TA₁	TAAR1	Human	Trace amine	A	pEC50	5.8	6.25	6.7	Guide to Pharmacology
TA₁	TAAR1	Rat	Trace amine	A	pEC50	6.9	7.05	7.2	Guide to Pharmacology
TA₁	TAAR1	Mouse	Trace amine	A	pEC50	6.2	6.65	7.1	Guide to Pharmacology
TA₁	TAAR1	Rat	Trace amine	A	pEC50	7.16	7.34	7.52	ChEMBL
TA₁	TAAR1	Human	Trace amine	A	pEC50	6.0	6.5	7.12	ChEMBL
TA₁	TAAR1	Human	Trace amine	A	pIC50	6.05	6.05	6.05	ChEMBL
TA₁	TAAR1	Mouse	Trace amine	A	pEC50	6.55	6.55	6.55	ChEMBL
TA₁	TAAR1	Human	Trace amine	A	pEC50	8.15	8.15	8.15	Drug Central
TA₁	TAAR1	Rat	Trace amine	A	pEC50	8.14	8.14	8.14	Drug Central
TA₁	TAAR1	Mouse	Trace amine	A	pEC50	8.15	8.15	8.15	Drug Central

Showing 1 to 11 of 11 entries