CHEMBL5090705


SMILES CCC(=O)N(c1ccc(Cl)c(Cl)c1)C1CCN(C(=O)[C@H](Cc2ccc(F)cc2)NC(=O)[C@H]2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2cc(C)c(O)c(C)c2)CC1
InChIKey AXIMWGIJSAJOAU-VDYROPKHSA-N

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Na
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pKi 8.0 8.0 8.0 ChEMBL
δ OPRD Human Opioid A pKi 8.92 8.92 8.92 ChEMBL
κ OPRK Human Opioid A pKi 7.55 7.55 7.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Rat Opioid A pIC50 7.64 7.64 7.64 ChEMBL
δ OPRD Human Opioid A pIC50 8.58 8.58 8.58 ChEMBL
κ OPRK Human Opioid A pIC50 7.01 7.01 7.01 ChEMBL