NALMEFENE-HCl


SMILES C=C1CCC2(C3CC4=C5C2(C1OC5=C(C=C4)O)CCN3CC6CC6)O.Cl
InChIKey GYWMRGWFQPSQLK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 375.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 9.52 9.52 9.52 PDSP Ki database
δ OPRD Human Opioid A pKi 8.14 8.14 8.14 PDSP Ki database
κ OPRK Human Opioid A pKi 9.52 9.52 9.52 PDSP Ki database
κ OPRK Guinea pig Opioid A pKi 9.52 9.52 9.52 PDSP Ki database
δ A0A286XTF2 Guinea pig Opioid A pKi 8.59 8.59 8.59 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database