CLOPROSTENOL
SMILES | C1C(C(C(C1O)C=CC(COC2=CC(=CC=C2)Cl)O)CC=CCCCC(=O)O)O |
InChIKey | VJGGHXVGBSZVMZ-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 5 |
Hydrogen bond donors | 4 |
Rotatable bonds | 11 |
Molecular weight (Da) | 424.2 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
FP | PF2R | Bovine | Prostanoid | A | pKi | 7.51 | 7.51 | 7.51 | PDSP Ki database |
EP3 | PE2R3 | Bovine | Prostanoid | A | pKi | 7.04 | 7.04 | 7.05 | PDSP Ki database |
EP1 | PE2R1 | Human | Prostanoid | A | pKi | 6.09 | 6.09 | 6.09 | PDSP Ki database |
DP1 | PD2R | Human | Prostanoid | A | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
EP3 | PE2R3 | Human | Prostanoid | A | pKi | 8.36 | 8.36 | 8.36 | PDSP Ki database |
EP4 | PE2R4 | Human | Prostanoid | A | pKi | 5.0 | 5.02 | 5.04 | PDSP Ki database |
FP | PF2R | Human | Prostanoid | A | pKi | 9.33 | 9.33 | 9.33 | PDSP Ki database |
IP | PI2R | Human | Prostanoid | A | pKi | 5.0 | 5.0 | 5.0 | PDSP Ki database |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |