WIN 55212-2


SMILES CC1=C(C2=C3N1C(COC3=CC=C2)CN4CCOCC4)C(=O)C5=CC=CC6=CC=CC=C65
InChIKey HQVHOQAKMCMIIM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 426.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CB2 CNR2 Mouse Cannabinoid A pKi 8.02 8.63 9.25 PDSP Ki database
CB2 CNR2 Rat Cannabinoid A pKi 7.98 8.44 8.89 PDSP Ki database
CB1 CNR1 Human Cannabinoid A pKi 7.2 7.54 8.01 PDSP Ki database
CB2 CNR2 Human Cannabinoid A pKi 8.68 9.11 9.54 PDSP Ki database
CB1 CNR1 Mouse Cannabinoid A pKi 9.39 9.39 9.39 PDSP Ki database
CB1 CNR1 Zebra finch Cannabinoid A pKi 7.2 7.2 7.2 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database