DADLE


SMILES CC(C)CC(C(=O)O)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)C(C)NC(=O)C(CC2=CC=C(C=C2)O)N
InChIKey ZHUJMSMQIPIPTF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 7
Rotatable bonds 15
Molecular weight (Da) 569.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
μ OPRM Human Opioid A pKi 8.55 8.55 8.55 PDSP Ki database
δ OPRD Human Opioid A pKi 9.74 9.74 9.74 PDSP Ki database
δ OPRD Mouse Opioid A pKi 8.74 8.74 8.74 PDSP Ki database
μ OPRM Bovine Opioid A pKi 7.85 8.07 8.29 PDSP Ki database
δ F1N083 Bovine Opioid A pKi 8.01 8.38 8.74 PDSP Ki database
δ A0A286XTF2 Guinea pig Opioid A pKi 8.72 8.72 8.72 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database