BP-897


SMILES COC1=CC=CC=C1N2CCN(CC2)CCCCNC(=O)C3=CC4=CC=CC=C4C=C3.Cl
InChIKey KFWJGUZIZAPFMX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 453.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.96 8.96 8.96 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 6.68 6.86 7.21 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 8.85 8.95 9.04 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 6.52 6.96 7.41 PDSP Ki database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.09 7.09 7.09 PDSP Ki database
D1 DRD1 Human Dopamine A pKi 6.12 6.12 6.12 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database