Tramazoline
SMILES | C1CCC2=C(C1)C=CC=C2NC3=NCCN3 |
InChIKey | QQJLHRRUATVHED-UHFFFAOYSA-N |
Chemical properties
Hydrogen bond acceptors | 3 |
Hydrogen bond donors | 2 |
Rotatable bonds | 1 |
Molecular weight (Da) | 215.1 |
Drug properties
Molecular type | Small molecule |
Endogenous/Surrogate | Surrogate |
Approved drug | No |
Bioactivities
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
α2A | ADA2A | Human | Adrenoceptors | A | pKi | 7.5 | 7.5 | 7.5 | PDSP Ki database |
α2B | ADA2B | Human | Adrenoceptors | A | pKi | 6.86 | 6.86 | 6.86 | PDSP Ki database |
α2C | ADA2C | Human | Adrenoceptors | A | pKi | 6.56 | 6.56 | 6.56 | PDSP Ki database |
α2A | ADA2A | Mouse | Adrenoceptors | A | pKi | 7.81 | 7.81 | 7.81 | PDSP Ki database |
α2A | ADA2A | Human | Adrenoceptors | A | pKi | 8.12 | 8.12 | 8.12 | Drug Central |
α2B | ADA2B | Human | Adrenoceptors | A | pKi | 8.16 | 8.16 | 8.16 | Drug Central |
α2C | ADA2C | Human | Adrenoceptors | A | pKi | 8.18 | 8.18 | 8.18 | Drug Central |
Receptor | Activity | Source | |||||||
---|---|---|---|---|---|---|---|---|---|
GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |